In addition, there was trend towards reduction of NFκB p50 mRNA in FcγR-/- SYN mice compared to FcγR-/- GFP mice, which did not reach statistical significance (Figure 3A and 3B ).
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Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.
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