While the administration of RU486 alone did appear to slow tumor growth somewhat in comparison to the DL70-3 and PBS controls, this effect did not reach statistical significance over the time course analyzed (the tumor volume for RU486 treatment at 8 weeks averaged 1989 ± 307 mm 3 ).
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Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice.
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