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Aromatase and 5-alpha reductase gene expression: modulation by pain and morphine treatment in male rats.

Mol Pain · 2010 · PMC2978140 · PMID 20977699

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[ 32 ] prospectively examined changes in cognition in hypogonadal men given T and older hypogonadal men given DHT; they demonstrated significant improvements in verbal memory in response to T supplementation with increased serum levels of T, DHT and E 2 (secondary to aromatization), although the increases in spatial memory did not reach statistical significance.

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