Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4.

Alzheimers Res Ther · 2010 · PMC2983440 · PMID 21062519

Europe PMC DOI

hedged sentence

0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

approaching significanceP = 0.076so close (0.05 < p ≤ 0.1)

In our studies of PSEN1 subjects, statin therapy reduced the phospho-tau values by 8.3% approaching significance ( P = 0.076) but with no significant changes in total tau or Aβ42.

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