We also noted that the velocity of cells migrating immediately below the endothelial monolayer tended to be slower in the presence of fibroblasts (6·8 ± 3·7 μm/min with dermal or 6·3 ± 2·1 μm/min with synovial co-cultures) compared with EC alone (9·0 ± 1·2 μm/min; mean ± SEM for three experiments), although this did not reach statistical significance.
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Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium.
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