High and increasing Oxa-51 DNA load predict mortality in Acinetobacter baumannii bacteremia: implication for pathogenesis and evaluation of therapy.

Interestingly, the nonsurvivors receiving appropriate empirical antibiotics showed a trend of no or less increase in Oxa-51 DNA compared with those receiving inappropriate empirical antibiotics ( P <0.001, Mann-Whitney U test, two tailed) (left panels, Figures 3B and 3C ).

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As shown in Figure 1 , a decreasing trend of the Oxa-51 DNA level was found in the survivors, whereas continuously high levels of Oxa-51 DNA were found in the nonsurvivors.

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