As expected, due to the strong correlation between ACPA and HLA-SE , carriage of HLA-SE alleles also strongly associated with erosive disease at 5 years ( Table 2 ). Only 2 of the 18 SNPs tested showed a trend towards association with the presence of erosions by Year 5.
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The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.
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