Patients with 1 copy of the HLA – DRB1 * 0401 allele had a higher mortality risk, although it did not reach statistical significance (HR 4.04 [95% CI 0.97–16.87]).
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Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.
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