Barely Significant
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Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.

Nucleic Acids Res · 2010 · PMC3001089 · PMID 20724444

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a clear trendno p-value reported
Rrm1 overexpression alone was able to induce a detectable, albeit not statistically significant, increase in dATP and dCTP levels, and overexpression of Rrm1 together with either small subunit led to a clear trend towards higher levels of dATP and dCTP.

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