Cytomorphological features of Hürthle cell carcinoma: A report of two cases with review of literature.

Second, in a majority of studies, it has not been possible to reliably distinguish between adenomas and carcinomas.[ 5 , 6 ] However, in these studies, there was a strong trend to suggest that many carcinomas could be distinguished from adenomas, and the problem always was a few carcinoma cases that lacked atypia or other specific features of malignancy.[ 6 ] Finally, to our knowledge, only a few studies included more than a few cases of carcinoma, thus making it difficult to assess the value of cytological features in making this distinction.[ 5 , 6 ] As the literature suggests, it is not always possible to distinguish HCCs from Hürthle cell adenomas.

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