Neurokinin-1 receptor antagonist treatment in polymicrobial sepsis: molecular insights.

SR140333 treatment, both 30 minutes before and 1 hour after CLP, showed a trend to reduce the phospho ERK1/2 levels, although the reduction was not statistically significant ( Figure 3(a) ). p-p38 and p-JNK MAPKs showed very weak signals and did not show significant differences between the groups (data not shown).

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