Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer.

Cancer Manag Res · 2009 · PMC3004662 · PMID 21188121

Europe PMC

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did not reach statistical significanceno p-value reported

Expression of both CD133 and LGR5, markers of colon cancer and colonic stem cells, and Wnt target genes, 34 , 35 decreased in normal mucosa following exposure to GP80 though the change in LGR5 did not reach statistical significance.

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