mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals.

PLoS One · 2010 · PMC3006197 · PMID 21200439

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

showed a trendP = 0.058so close (0.05 < p ≤ 0.1)

In contrast, levels of IL-2, IL-6, IL10, IL-12, and GM-CSF showed no significant change while TNF-α showed a trend toward lower levels with rapamycin treatment (P = 0.058).

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