The injection of the prodrug resulted in reduced tumor size in all subgroups when compared with the corresponding non-prodrug-treated animals, although the difference did not reach statistical significance in those groups injected with PBS or the GLV-1h43 strain ( P >0.15).
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Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a β-galactosidase-activatable prodrug seco-analog of duocarmycin SA.
1
0.1500
0.1500