The role of glutamate receptor redistribution in locomotor sensitization to cocaine.

A trend toward decreased locomotor counts during the late phase was present in the 0.3 μg CNQX-Coc group, but it did not reach statistical significance, regardless of whether we compared the Veh-Coc group and the 0.3 μg CNQX-Coc group across 40–70 min using repeated measures ANOVA ( Figure 9c , open circles vs closed squares, 40–70 min; main effect of group, F (1,70) =1.9; p =0.18; group × time interaction, F (5,70) =0.5; p =0.18) or simply compared the Veh-Coc group and the 0.3 μg CNQX-Coc group during the late phase with an unpaired t -test ( Figure 9d ; t 14 =1.38, p =0.19).

also in 111,027 other papers

GluR2 distribution was not significantly altered by cocaine challenge in either saline- or cocaine-pretreated groups, although there was a small trend toward decreased S/I ( Figure 5b ).

also in 722 other papers