There was a trend toward increased fibrosis in the hearts of treated mdx mice (mdx S % fibrosis 0.68 ± 0.47), compared with controls (mdx C % fibrosis 0.14 ± 0.071), but this did not reach statistical significance ( P > 0.05).
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Long-term blocking of calcium channels in mdx mice results in differential effects on heart and skeletal muscle.
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