Exercise induced highly significant rises in glycogen synthesis rates in both groups, but the increase in obese subjects was reduced compared with lean (112 ± 15 vs. 186 ± 27 μmol/kg muscle/min; P = 0.03), although the relative increase was similar (184 ± 35 vs. 202 ± 51%; P = 0.78).
When all data are included, no significant correlation is present ( r = 0.40, P = 0.10), but this correlation becomes borderline significant ( r = 0.47, P = 0.06) upon exclusion of the two outlying data points of the subjects with the two highest values for whole body glucose uptake.
The difference in baseline glycogen synthesis rates approached significance ( P = 0.07) with 78 ± 14 and 132 ± 24 μmol/kg muscle/min for obese and lean subjects, respectively.