Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency.

PLoS One · 2011 · PMC3020968 · PMID 21249153

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In the neostriatum, CrT −/y mice showed a trend towards increased DA (F(1,16) = 3.64, P<0.10); they had increased levels of 5-HIAA (F(1,16) = 12.41, P<0.01) and 5-HIAA/5-HT (F(1,16) = 11.63, P<0.01) compared with CrT +/y mice.

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