Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.

Int J Alzheimers Dis · 2010 · PMC3021864 · PMID 21253550

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showed a trendno p-value reported

There was no significant effect of these compounds in the γ -secretase assay, although thiorphan showed a trend for an increase in AICD signal.

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