Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.

PLoS One · 2011 · PMC3022633 · PMID 21267448

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failed to reach statistical significanceno p-value reported

For the PTEN −/− cultures the average pAkt increase was 24.46% but failed to reach statistical significance, which can be partially explained with already high levels of pAkt due to PTEN-deficiency.

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