However, at this time point in the present study, immunohistochemical staining of P-gp expression in the hippocampus revealed only a small trend in kainate treated rats.
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(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus.
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The sentences
The area method showed a trend towards higher P-gp expression in kainate treated rats, although the large variation resulted in a non significant difference when groups were compared with the student's t-test (p > 0.05).