Circulating endothelial cells are an early predictor in renal cell carcinoma for tumor response to sunitinib.

BMC Cancer · 2010 · PMC3023793 · PMID 21194438

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showed a trendno p-value reported

While, baseline values of CEC prior to drug exposure showed a trend to lower values (40 ± 41 CEC/ml) in patients with a PFS above the median when compared to patients with a PFS below the median (53 ± 45 CEC/ml), these differences remained insignificant (P = 0.4414) and do not explain treatment outcome as a single pre-dose evaluation.

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