Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsia.

PLoS One · 2011 · PMC3031618 · PMID 21304959

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

approached significanceP = 0.061so close (0.05 < p ≤ 0.1)

However, when both maternal and fetal terms were included in the same model, again the fetal association decreased in significance ( P = 0.561) and the maternal ordered COMT haplotypes approached significance ( P = 0.061).

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