14 , 32 Immunoblotting analysis of cortical mitochondrial fractions showed a slight increase in the dimeric BNip3 signal in the R6/2 striatum than in the wild-type striatum, but the difference did not reach statistical significance ( Figure 2d ).
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Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3).
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