Endogenous nociceptin / orphanin FQ system involvement in hypothalamic-pituitary-adrenal axis responses: relevance to models of inflammation.

J Neuroendocrinol · 2009 · PMC3034194 · PMID 19732291

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

just failed to reach significanceP < 0.05actually significant

Post-hoc tests revealed a significant increase in CRF expression induced by only the Sal/LPS group because the trend towards an increase seen with the UFP/LPS group just failed to reach significance (Sal/Sal: 100.0 ± 19.84%, n = 9; Sal/Sal: 99.49 ± 16.67%, not significant, n = 7; Sal/LPS: 182.5 ± 28.57%, P < 0.05, n = 7; UFP/LPS: 167.7 ± 24.20%, not significant, n = 8).

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a clear trendno p-value reported

Intracerebroventricular UFP-101/LPS treatment was associated with increased POMC mRNA expression 4 h after injection and a clear trend towards increased parvocellular CRF mRNA.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.