PKC-ε decreased significantly in males ( P = 0.006) and showed a trend to decrease in females (Fig. 3 ).
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Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.
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Three PKC isoenzymes were also tested, and PKC-α and PKC-δ were found to be significantly upregulated after Ang II treatment whereas expression of PKC-ε showed a slight trend to decrease.