There was a strong trend towards base substitutions and frameshifts at purine sites in the mutations induced by the extract in Escherichia coli (CC103 and CC104 strains) and Salmonella typhimurium test strains (22-fold increase in histidine revertants in TA98 strain).
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Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts.
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