MCMV-induced weight loss and liver pathology in mrIL-10 treated versus untreated IL-10 KO mice Untreated IL-10 KO mice showed a trend toward suffering increased MCMV-induced weight loss compared to mice repleted with mrIL-10 (Fig. 6 ).
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Interleukin-10 repletion suppresses pro-inflammatory cytokines and decreases liver pathology without altering viral replication in murine cytomegalovirus (MCMV)-infected IL-10 knockout mice.
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