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Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop.

BMC Emerg Med · 2011 · PMC3042971 · PMID 21291549

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a clear trendno p-value reported
The targeted clinical response is often termed, "initial control of the envenomation syndrome," and consists of arrest of the progression of local tissue venom effects, a clear trend toward improvement in any hematologic venom effects, and resolution of all systemic venom effects (excluding fasciculations or myokymia, which may be refractory to antivenom [ 7 , 11 ].

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