Eurasian and Sub-Saharan African mitochondrial DNA haplogroup influences pseudoexfoliation glaucoma development in Saudi patients.

Mol Vis · 2011 · PMC3044700 · PMID 21364909

Europe PMC

hedged sentences

0.0650

closest p · 1.3× alpha

0.1780

boldest claim

The sentences

near significancep=0.065so close (0.05 < p ≤ 0.1)

Statistically, this abundance was significant for the L2 haplogroup (p=0.008) and near significance for the T haplogroup (p=0.065).

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did not reach statistical significancep=0.178not close (p > 0.1)

Pair-wise exact tests between cohorts showed that this statistical heterogeneity is mainly due to particular differences between PEG versus HMC (p=0.016) and PEG versus HSA group (p=0.027) as haplogroup differences between both control groups did not reach statistical significance (p=0.178). χ 2 or two tailed Fisher exact tests analysis of haplogroup frequencies in PEG patients versus HMC group indicate that haplogroups T and L2 were in significant excess in PEG patients compared to HMC (p=0.025 and p=0.045, respectively).

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