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Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model.

Arthritis Res Ther · 2010 · PMC3046537 · PMID 21190566

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showed a trendno p-value reported
Male mice were used because they showed a trend to higher arthritis severity compared with female mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.