BMI (HR 1.03 [95% CI 0.99–1.06], P = 0.08), hypertension (1.50 [95% CI 0.99–2.27], P = 0.054), and sex (1.30 [95% CI 0.95–1.79], P = 0.10) also tended to be associated with increased rate of events, although these did not reach statistical significance.
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The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients.
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