Candesartan cilexetil/hydrochlorothiazide combination treatment versus high-dose candesartan cilexetil monotherapy in patients with mild to moderate cardiovascular risk (CHILI Triple T).

Differences were highly significant compared with baseline ( P < 0.0001) and significant for the difference between systolic blood pressure values ( P = 0.011).

also in 132,142 other papers

38 – 42 In the present trial, patients on candesartan experienced higher reductions in microalbuminuria in the candesartan high-dose arm compared with the candesartan and HCTZ combination treatment arm, although this change did not reach statistical significance.

also in 111,027 other papers

Differences in subgroups of patients defined by age, gender, body mass index, dyslipidemia, waist circumference, smoking, prior cardiovascular event, glomerular filtration rate, and microalbuminuria were minor, although partially significant.

also in 417 other papers