A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

In the first stage of this GWAS, we observed a moderately significant effect for rs401681 ( P = 2.9 × 10 −3 ), which was at genome-wide significance when combined with the Rafnar et al. data ( P = 5.0 × 10 −7 ; OR per C allele 1.11, 95% CI 1.07-1.16) ( Table 1 , Supplementary Figure 3 ).

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