Genetic characteristics, coreceptor usage potential and evolution of Nigerian HIV-1 subtype G and CRF02_AG isolates.

There is no previous data on HIV-1G tropism, thus it was interesting to note that all the five methods showed a trend toward higher usage of CXCR4 in HIV-1G in comparison to CRF02_AG and individually, was found to be statistically significant (p = 0.007, Fisher's exact test) using the combined criterion ( Figure 3b ), which has previously been shown to perform best for the prediction of CRF02_AG coreceptor usage [41] .

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