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N-acetylcysteine and N-nitroarginine methyl ester attenuate Carboplatin-induced ototoxicity in dissociated spiral ganglion neuron cultures.

Clin Exp Otorhinolaryngol · 2011 · PMC3062221 · PMID 21461057

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Addition of L-NAC or L-NAME reduced the amount of carboplatin-induced hair cell damage; the differences did not reach statistical significance.

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an increasing trendno p-value reported
However, there was an increasing trend of survival of the OHCs after administration of L-NAME or L-NAC; however, the changes did not reach statistical significance.

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