Location of immunization and interferon-γ are central to induction of salivary gland dysfunction in Ro60 peptide immunized model of Sjögren's syndrome.

Although the addition of PTX to MAP-Ro60 immunized mice compared to PBS controls tended to increase the mean focus scores for the tailbase (0.88 versus 0.42, p = 0.15) and abdominal area (0.59 versus 0.36, p = 0.20) injection sites, this increase did not reach statistical significance ( Figure 3 ).

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