North African influences and potential bias in case-control association studies in the Spanish population.

However, while the North African influence in Iberian populations has been estimated in 8–10% based on markers with uniparental inheritance [6] , [12] , [13] , we found slightly lower levels using autosomal markers, ranging from as low as 2.1% (SD = 4.6) in Eastern Iberians to as much as 9.0% (SD = 23.8) in Western Iberian samples, although these differences did not reach statistical significance (two-tailed t-test p = 0.156).

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