Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity.

BMC Endocr Disord · 2011 · PMC3070678 · PMID 21426570

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 1.62 × 10 -6actually significant

Highly significant enrichment was uniquely found within the first quartile of ranked genes, including transcription regulation (p < 1.62 × 10 -6 ) and regulation of cellular metabolic processes (p < 4.3 × 10 -4 ).

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showed a trendno p-value reported

While this clearly has limitations, six miRNAs showed a trend for a stronger upregulation during white pre-adipocyte differentiation compared with brown pre-adipocytes, while another 6 miRNAs showed a trend for a stronger upregulation during brown pre-adipocyte development (see Figure 1 ).

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