Data from this experiment again revealed a highly significant reduction in overall activity in the BAC TG mice, t (61) = 11.3, p < 0.001, while also indicating a more pronounced shift in the activity peaks, as seen in the lower panel of Figure 2.
Note that the peaks of activity of the BAC groups were progressively shifted toward later times as expected from the circadian FF analysis (Figure 4), but in these data the period differences failed to reach significance, t (6) = 1.67, p > 0.1.
There was also a significant overall effect of days and a significant interaction between light/dark phase and days, smaller F (4,196) = 6.02, p < 0.0001, but no other effects or interactions approached significance, larger F (1,49) = 1.61, p > 0.2, F (4,196) = 1.60, p > 0.15.