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Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain.

J Neuroinflammation · 2011 · PMC3077319 · PMID 21453520

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It is interesting to note that atorvastatin treatment alone caused a slight increase in expression of CD161, CD11b, MHCII, and IP-10, although this increase did not reach statistical significance; these effects are apparently independent of IFNγ and NKp46.

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