Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production.

Reduction of I-Aβ, presumably a result of class II MHC complex degradation, was seen in both WT and KR mice; however, the degradation of class II MHC tended to be greater in the WT mice ( Figure 3B and 3C ) in the three times that this experiment was performed, but the differences did not reach statistical significance.

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