Predictors of the risk of cognitive deficiency in very preterm infants: the EPIPAGE prospective cohort.

The difference in odds ratios for mild versus severe cognitive deficiency was not statistically significant for parents’ socio-economic status and bronchopulmonary dysplasia (p-value for heterogeneity in odds ratios = 0.4 and 0.2, respectively) but was almost significant for cerebral lesions and number of siblings (p-value for heterogeneity in odds ratios = 0.08 and 0.1, respectively) and significant for gestational age of 28 weeks or less and small for gestational age (p-value for heterogeneity in odds ratios = 0.01 and 0.007, respectively).

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Bronchopulmonary dysplasia was associated with mild cognitive deficiency, although this association did not reach statistical significance (odds ratio: 1.57; 95% CI: 0.97–2.54) ( Table 2 ).

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