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RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells.

J Biomed Sci · 2011 · PMC3080799 · PMID 21453546

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Similarly, the cell viability of EGFP-transduced MCF-7 cells after 1 to 4 days rADI treatment was 89% to 77% of the controls, a decrease that failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.