Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps.

In the remaining two groups, although exacerbations were numerically lower with BUD/FORM maintenance and reliever therapy the differences did not reach statistical significance (GINA treatment Step 2 patients vs. higher maintenance dose ICS + SABA [0.144 vs. 0.174], and GINA treatment Step 3 patients vs. higher maintenance dose ICS/LABA + SABA [0.198 vs. 0.250]) (Figure 3 ).

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