Treatment with EN277I increased the current by 48% (1.14 ± 0.08 μA/cm 2 , n = 6), but the effect did not reach statistical significance ( p > 0.05).
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Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.
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