Previous comparative microarray analysis of CD44+/CD24-/lineage- cancer cells and normal breast epithelial cells revealed specific increased expression of SLUG in the CD44+/CD24- subpopulation, although differences did not reach statistical significance due to small sample size (3 samples for non-CD44 and five samples for CD44+ tumor samples, p = 0.054) [ 13 ].
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SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.
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