Are behavioral effects of early experience mediated by oxytocin?

Front Psychiatry · 2011 · PMC3098714 · PMID 21629841

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0560

boldest claim

The sentences

marginally significantp = 0.051so close (0.05 < p ≤ 0.1)

OTR binding in females was also marginally significant in the same direction in the cingulate cortex ( F 3 = 2.89, p = 0.051; optical densities, MAN1 = 0.107 ± 0.03, MAN1–7 = 0.115 ± 0.02, MAN7 = 0.126 ± 0.3, MAN0 = 0.248 ± 0.06) and the lateral septum (LS; F 3 = 2.97, p = 0.054; optical densities, MAN1 = 0.114 ± 0.03, MAN1–7 = 0.15 ± 0.02, MAN7 = 0.181 ± 0.7, MAN0 = 0.289 ± 0.09).

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approached significancep = 0.056so close (0.05 < p ≤ 0.1)

However, planned comparisons between MAN0 and MAN1 groups revealed that the differences in density of AVP immunoreactive cell bodies approached significance ( F 1 = 4.34, p = 0.056) with high levels of AVP in MAN0 versus MAN1 males.

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