A polymorphism in the regulatory region of PRNP is associated with increased risk of sporadic Creutzfeldt-Jakob disease.

BMC Med Genet · 2011 · PMC3114709 · PMID 21600043

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showed a trendno p-value reported

In agreement with our multivariate analysis, the stratified analysis of PRNP G310C across the PRNP M129V genotypes showed a trend in all three strata to a higher proportion of individuals with PRNP 310C allele in the sCJD cases than in the controls.

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