OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62.

PLoS One · 2011 · PMC3115989 · PMID 21698267

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quite significantno p-value reported

Thus, even moderate down-regulation of LDL-R might lead to a quite significant elevation of LDL cholesterol.

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